glp-1 for nash The Emerging Role of Glucagon-Like Peptide-1 Receptor Agonists the Treatment of Metabolic Dysfunction-Associated Steatohepatitis Sodium butyrate reduces high-fat diet-induced

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doi: 10.1016/j.phrs.2022.106320 29 LeRNguyenMTAllahwalaMAPsaltisJPMaratheCSMaratheJAet al

In addition to its extensively studied actions in peripheral tissues, studies have evaluated the distribution of GLP-1R in the central nervous system (CNS) of rodents, non-human primates, and humans, showing that it is widely diffused to multiple CNS neurons including neurons of the arcuate nucleus (ARC), which are crucial for the control of energy balance (Fig